Gastrin cells and fasting serum gastrin levels in duodenal ulcer patients
نویسنده
چکیده
The number of gastrin-producing cells in biopsy specimens from the gastric and duodenal mucosae in 19 duodenal ulcer patients was quantitated using a morphometric method. The level of immunoreactive gastrin in a sample of fasting serum obtained at the time of the biopsy was measured by radioimmunoassay. The results show no significant difference when compared with those from a group of normal control volunteers. Moreover, there was no correlation between the numbers of gastrin-producing cells and the fasting serum gastrin level in either controls or duodenal ulcer patients.
منابع مشابه
Serum gastrin in patients with peptic ulceration.
The fasting serum level of gastrin was determined by radioimmunoassay in 41 normal subjects, 27 patients with duodenal ulceration, 12 patients with gastric ulceration, and 8 patients following "complete" vagotomy. The patients with duodenal ulceration had significantly higher serum levels of gastrin (1.3 +/- S.D. 0.7 ng./ml.) than normal subjects (0.4 +/- S.D. 0.3 ng./ml.), patients with gastri...
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